Forces in the Respiratory System Normal Chest AnatomyKey Words chest lungs fx normal chest CT anatomy45771Ashley Davidoff MD TheCommonVein.net Keeping the Lungs attached to the Chest Wall via A Two Layered Pleura – Capillary ForcesThe coronally reformatted image of the lung parenchyma has been outlined with the visceral pleura, (pink) the pleural fluid in the pleural space, (orange) and the parietal pleura. (green) Note how at end expiration the parietal pleura in the costophrenic sulcus extends beyond the lung margin so that the visceral pleura is absent in the costophrenic sulcus and there are two layers of parietal pleura facing each other. During inspiration the lung expands into this space. 32634b10Key Words lung pleura pulmonaryAshley Davidoff MD TheCommonVein.net Mechanical Forces Bringing Air to AlveoliChest Wall, Diaphragm, Alveolar ExpansionThe five major layers that keep the air moving include the outer bony cage, the muscular layer represented in maroon, the pleural complex (orange yellow orange) the lung (blue) and surfactant within the alveolus. (pink)42530b05b09b01a08 Ashley Davidoff MD TheCommonVein.net Chemical Force of Surfactant to Keep the Alveoli Open during RespirationThis a grape like cluster of normal alveoli. Key words lung alveolus terminal bronchiole respiratory bronchiole RS normal anatomy drawing 32163Ashley Davidoff MD TheCommonVein.net Oxygen Gradients Created by the Lungs Across the Alveolar MembraneThis diagram again shows the alveolus in teal, the arteriolar component of the capillary with red cells in blue and venular component replenished by oxygen in red. As noted above, the PO2 of the arterial blood is 40mmHg while the inspired air is 104mmHg. A pressure gradient thus exists and diffusion from the high to the low pressure occurs with a net movement of oxygen into the blood to equilibrate the pressure. Venous blood is now rich in oxygen with a PO2 of 104mmHg.42445b08bAshley Davidoff MD TheCommonVein.net Fluid Gradients at the Capillary LevelKey Words capillary interstitium arteriole arteriolar pressure capillary pressure venule venular pressure interstitial pressure colloid osmotic pressure plasma colloid osmotic pressure Forces tending to move fluid out of the capillary is capillary pressure of 25mmHg, negative interstitial pressure = 6mmHg and and interstitial osmotic pressure of 5 mmHg = total of 36mmHg Forces holding the holding the fluid in the capillaries include the plasma oncotic pressure of 28mmhg and thus the net outward force is about 8mmHg42445b03d06Ashley Davidoff MD TheCommonVein.net